Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden

Isolated pulmonary embolism in a patient with progestin intrauterine device and factor V Leiden

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The risk of venous thromboembolism (VTE) in patients using estrogen contraception is well known.However, the association of progestin-only contraception (POC) and the risk of thrombosis is poorly investigated.Few studies on this topic have failed to prove a significant increase in VTE in patients using POC, including patients with a medical condition associated with an increased risk of thrombosis.Therefore, no specific consideration is warranted when using a POC in healthy young females, Amplifier Installation Kit regardless of an inherited thrombophilia.

We present a case of a young woman who has Factor V Leiden (FVL), presenting with an isolated pulmonary embolism (PE) while using a progesterone containing Bags intrauterine device (IUD).The risk of VTE in FVL carriers seems to outweigh the benefit of contraception even when using progestin-only contraception.Therefore, non-hormonal contraception, such as copper IUD, seems to be the only safe alternative for contraception in this population.Further studies are needed to elucidate this observation.

Abbreviation: PE: pulmonary embolism; FVL: factor V Leiden; VTE: venous thromboembolism; POC: progestin only contraception; CBC: complete blood count; CMP: complete metabolic panel; ABG: arterial Blood gas; CTPA: CT pulmonary angiography.